Oxymetholone: How is it used

In one of the forum where I am firmly entrenched, the idea to organize an all-out copy-paste all more or less useful information, which can be found in the vast foreign steroid publications. Editor article made lance, for which he thank you.

I would just mention that the presented information is a creative recycling I have read, there are few original thoughts, I was just trying to convey what seemed important. You’d be surprised, but I will not compel the importance of the PCT, and the suppression of endogenous testosterone. :)

Hopefully useful forum users. Strongly do not beat. :)

Probably, it is already clear from the title, which will focus on the 50-oxymetholone (Anadrol-50, Anadrol-50 androlik-50)

Like many other drugs used in bodybuilding, oxymetholone-50 (hereinafter – oxymetholone) began his career as a medicament for the really sick people.

Year of birth oksimetolona- 1960 place rozhdeniya- US (and someone says, Mexico), pharmaceutical concern Syntex. Initially oxymetholone proved himself an excellent tool for the treatment of various types of anemia, its reception has stimulated production in patients with endogenous erythropoietin, thereby greatly increased the number of red blood cells in the blood. On the same property due to use of oxymetholone to treat many types of blood cancer. With the advent of synthetic erythropoietin Syntex has stopped production and distribution of the drug in the US in 1993, and after a while oxymetholone has been removed from the range in other countries. Athletes around the world with horror apprehended the final withdrawal of the drug in their lives. And all would have been bad if it were not for HIV / AIDS. To the delight of the sports community, research in this direction made shine oxymetholone their new faces. Was discovered his amazing ability to prevent muscle loss in patients with HIV / AIDS, on top of that was obtained conclusion about the relative safety of its use in such cases (1). Interest has been so strong that in 1998 oxymetholone again sold in the United States.

 

Brief Description of the drug

Activity: at least 16 hours

Classification: Anabolic / Androgenic Steroids

The appearance of acne: yes

Water retention: very high

High Blood Pressure: Yes

Hepatotoxicity: moderate

Aromatization not flavored

DHTkonvertatsiya: is a derivative of DHT

Suppression HPTAfunktsii: very large

 

The opinion of people

Oxymetholone is considered terribly harmful drug. Everyone is convinced that simply did destroy the liver, it covers athletes thick, like Chewbacca, hair, causing baldness. A few weeks after the testicles and reception at all hard to find. See more here

“Glory” and oxymetholone monstrous ability to retain water in the body of an athlete. However, most athletes use it at all does not spoil the mood, because they feel so much power, and they see in the mirror taaaaaakie metamorphosis that any counter fade. The muscles become more “filled”, the athletes say incredible feeling pump during training. This avalanche increase in body weight may play a cruel joke with the athlete. It is no secret that the muscles and tendons grow at different rates. Breaks pectoral muscles and torn biceps – typical injuries lovers oxymetholone.

 

How is it used

The most important question for the readers. In most cases, oxymetholone used during bulking, the off-season. It is used at the beginning of long-term steroid course sharply to “run” the work of the entire set of medicines. It works very quickly, exhibits its activity almost immediately, while noting its synergies with other steroid compounds. This happens largely due to lower property oxymetholone levels of sex hormone binding globulin (2) and its poor ability to join the androgen receptor (3).

As a rule, the starting dose is 50 mg of oxymetholone per day, for many “bodybuilding enthusiasts” and it would be sufficient. But some may need to increase the dosage to 150 mg per day. The bravest people manage to eat it and 300 mg per day. It is worth noting that very few athletes notice any changes in comparison with the dosage of 150 mg per day, provided the use of the drug in combination with other AAS.

The only advice we can give here – is to increase the dosage to wait at least a couple of days to make sure you really do not have the current dosage of the drug. It should be noted that at 100 mg per day oxymetholone many users generally lost appetite.

Duration Admission oxymetholone should not exceed 4-6 weeks. Not so much because of the negative effects on the liver (which is greatly exaggerated, and that I will discuss later), but more because of the fact that after 6 weeks of use it starts to sharply reduce the efficiency. In fact, peak efficacy of the drug is observed up to the 4th week of reception. Then, says quite a sizeable drop in returns, which leads many athletes “gesture” with dosages. 4 weeks oxymetholone has done its job, and will have to pass the baton to other drugs in combination that you use. What to put it? Oxymetholone should always be placed on the course, in combination with a large dose of testosterone. Together they give an impressive effect. You can also add in the course of any nandrolones and trenbolone.

Some athletes used the drug in the drying phase (I do not understand how, but it’s true, apparently large doses of aromatase inhibitors, antiestrogens and diuretics solve the problem). Oxymetholone allows athletes to maintain muscle fullness, even under very strict diet. It must be remembered here that, as previously mentioned, the drug is highly water retention. And its proper use in the final phase of preparation for a competition depends primarily on the experience of the athlete. This drug does not forgive errors in the diet. As a rule, the reception begins 4 weeks before the show, dozirovka- minimum of 50 mg per day. For a couple of hours before going on stage Athletes often use oxymetholone in a shock dosage of 300-400 mg.

 

With that said doses of oxymetholone official science

Oxymetholone is one of the few steroids, which plot of “dose-effect” flattens out very quickly. From 50 mg daily gain is simply good. If you take 100 mg a day or gains will have “very” good. But from 150 mg daily gain is the same as the previous dosage, but the likelihood of side effects increases (4).

 

Oxymetholone and women

Despite the fact that many consider the most terrible drug oxymetholone based on the possibility of virilization symptoms, practice proves the opposite. Medical studies in women oxymetholone use a dose of 50 mg per day for a long time showed only a moderate risk of virilization symptoms. In fact, this risk is considered lower than that of methandrostenolone, stanazolola and even oxandrolone (fans of “the cleanest and safest in the world steroid” can begin to spit in the monitor).

Of course, the daily dose of 50 mg by the standards of contemporary women’s competitive bodybuilding can not be considered high, but for most athletes, it will be sufficient to achieve good results. Even a dosage of 25 mg of oxymetholone per day for female athletes to be very effective, while carrying almost zero probability of occurrence of side effects. It is worth noting that the low risk-it’s still a risk. More information

Girls, do not eat well, you steroids!

 

Side effects

Oxymetholone was always surrounded by horror stories about the crazy side effects. The majority pobochek emerge when estradiol levels in the body are inflated. It is interesting that the drug is not flavored, because it is a derivative of dihydrotestosterone (yes, contrary to popular opinion oxymetholone is not a derivative of nandrolone). There is much speculation as to why his appointment is accompanied by the occurrence of estrogenic side effects.

Indeed, it is very frequent ginekomastiya- satellite athlete on oxymetholone. It argued that it has progestogenic activity, similar to nandrolone. As the side effects of estrogens and progestins are very similar, and at first glance it seems plausible version. But, fortunately, there are medical studies that shed light on this question. During one of these checks for progestagenic activity of various steroids including nandrolone, norethandrolone, methandrostenolone, testosterone and oxymetholone. Conclusions uniquely studies suggest that no significant progestational effect not demonstrated any oxymetholone or methandrostenolone. Partly progestogenic activity was observed in the testosterone and strong – from nandrolone and norethandrolone. So, anyway, the indisputable fact is that if the level of estradiol in the body is under control, the fear of serious side effects of oxymetholone is not necessary. In this case, estradiol is best monitored using aromatase inhibitors, or by using too high dosages aromatizing agents (which, of course, reduce the efficiency massonabornogo rate). If the moment upuschen- will have to use anti-estrogens, such as Clomid, tamoxifen and toremifene.

Oxymetholone – a very potent androgen. Oily skin, acne and hair growth on the face and all over my body with this drug is normal. Many athletes react to the reception of severe acne, get rid of that, you can often just using isotretinoin (Roaccutane). Those who have a predisposition to baldness, and who loves his remaining hair better that do not look in the direction of oxymetholone general. During the course, the hair falls out with frightening speed. Paradoxically, oxymetholone is subject to conversion to dihydrotestosterone, a derivative of which it is, although it is not going through the 5-alpha-reductase. Oxymetholone differs from DHT only added 2-hydroxymethylene group. The human body is transformed into oxymetholone potent androgen 17alpha-methyl dihydrotestosterone (Mesterolone; methyldihydrotestosterone). And no inhibitors of 5-alpha reductase will not help.

You should specifically mention the following fact: in the course of clinical studies have found that high doses of oxymetholone increase insulin resistance (5).

 

Oxymetholone and liver

I decided to put the issue beyond the section of such effects as hepatotoxicity monstrous oksimetolona- is one of the biggest zabluzhdeniy.Na each corner shouting about its terrible effects on the liver.

Milligram to milligram, oxymetholone actually even less hepatotoxic than any other 17-alpha alkylation of the steroid, it is simply used in much larger than other similar drugs dosages. To avoid possible serious problems by limiting the period of use of the drug 6 weeks (a standard recommendation for any 17-alpha-alkylation product).

 

We are faced their foreheads

Any reader of this article will wonder about what kind of drugs are effective – methandrostenolone or oxymetholone. You can only rely on practice. For this post, I found a man who shared his thoughts.

So the impression of oxymetholone and methandrostenolone reception from the mouth of competitive athletes. In patients receiving the combination of testosterone enanthate and decanoate nadrolona at different times it included oksimetolon- four weeks at a dose of 50-100 mg per day, methandrostenolone and the same term in a dosage of 50-75 mg per day.

Power: both drugs provided identical to a significant increase in power performance.

Endurance: methandrostenolone has shown himself better. Cardio and general muscular endurance on oxymetholone been much worse.

Pumping: On the first week of admission oxymetholone seemed that in training skin may just burst. Methandrostenolone also provides a good pump, but pumped by oxymetholone it any comparison does not go. On oxymetholone it had to significantly reduce training hand because of the wildly painful pump.

Weight gain: Oxymetholone gave 2 kg gain for the first week of admission, but the overall result was much the same as methandrostenolone. Methandrostenolone first week only grows in the body, and then a good gain in body mass and strength. The overall increase in both cases was 8 kg.

Appetite: Methandrostenolone here was better, it would be desirable to have all the time. Oxymetholone at a dosage of 100 mg completely suppress your appetite (and we already subtracted). Even though, that the protocol Reception present GHRP-6, which stimulates the appetite. Reducing the dosage to 50-75 mg of oxymetholone per day returned to their seats.

Side effects: It is amazing, but there was better oxymetholone. Because of the strong flavoring methandrostenolone prhodil taking high doses of aromatase inhibitors. And oxymetholone not required, and the dosage of testosterone remains the same. AROMASIN in a daily dosage of 12.5 mg happy with it.

General feeling: Methandrostenolone is competition for him in a good mood, feeling great. Oxymetholone makes a person sleepy, but larger doses do feel just awful.

I think every man for himself will draw conclusions on their own.