Oxymetholone Side effects associated with estrogen activity

Oxydrol tablets – a synthetic anabolic steroid developed in 1960 by Syntex Pharmaceuticals. Initially, Oxymetholone developed as a drug for the treatment of osteoporosis and anemia (anemia), as well as to stimulate muscle growth in malnourished and debilitated patients. Oxymetholone was approved by the FDA for use in humans. Later, non-steroidal drugs have been developed that effectively treat anemia and osteoporosis, due to which the popularity of Oxymetholone fell and by 1993 Syntex decided to stop production of the drug, as well as other manufacturers. However oxymetholone still remained in medicine, as new research has shown that Oxymetholone is effective in the treatment of HIV-infected patients.

Oxymetholone available in tablets of 50 mg and is one of the most powerful steroid available, at the same time, the drug can cause some side effects, characteristic of all anabolic steroids.

The steroid profile

  • Anabolic activity – 320% of testosterone
  • Androgenic Activity – 45% of testosterone
  • Aromatization (conversion to estrogen) – No, but he has an estrogenic effect
  • Liver toxicity – moderate
  • A method of receiving – by mouth (tablets)
  • Duration – 15 hours
  • Detection time – up to 8 weeks

Oxymetholone Effects

  • Severe muscle growth (oksimetalon considered one of the most effective steroids in bodybuilding for muscle set – up to 15 kg of muscle mass for 1 course after course of seen significant rollback phenomenon – up to 30% of the gain weight may be lost, given that some weight gain is due to accumulation of fluid)
  • Significant increase in strength
  • Anapolon eliminates joint pain and improves their function (due to fluid retention and greater output of synovial fluid)
  • Reduces the sex hormone binding globulin – it makes the effect of other hormones in the combined use of a more pronounced

The side effects of oxymetholone

In general, the relative oxymetholone rarely causes adverse effects. If we compare the ratio beneficial effects / side effects, that can be called Anapolon be the best anabolic steroids, provided that the price of the drug is quite low. The low incidence of side effects of the drug at a dose of 100 mg per day, supported by research.

17aa changes in the structure of the drug makes it possible to pass through the liver without being destroyed, it also makes Oxymetholone toxic to the liver. Studies have been conducted in a duration of 30 weeks, where the subjects used Oxymetholone 50 mg and side effects were noted on the liver. However, we must pay tribute to that in a study involving patients with HIV and duration of admission was 30 weeks. Passing a standard 4-6 week course Oxymetholone liver in most cases remains intact.

Oxymetholone Side effects associated with estrogen activity are still questionable. The fact that oxymetholone not converted into estrogen, nevertheless can cause fluid accumulation in the body to raise blood pressure and others. It is assumed that Anapolon can itself bind and activate the estrogen receptors. Read more

In some cases (when using large doses of) the drug can impair appetite, cause mild nausea.

Oxymetholone is less than most steroids suppresses the production of testosterone.

Oxymetholone course

  1. The course is suitable Oxymetholone men over 21 years for intensive recruitment of muscle mass.
  2. The duration of oxymetholone is 4 -6 weeks. Do not longer than 6 weeks of course, firstly because the greatest results observed during the first three weeks of the course, and secondly, because of the potential for liver toxicity.
  3. Include in the course of Oxymetholone 10 mg of Nolvadex 1 time per day for blocking estrogen effect of the drug.
  4. Maximum Dosage Oxymetholone – 100 mg per day. Firstly, because it has been proven that a greater increase in dosage does not lead to better results. Secondly, the risk of side effects Oxymetholone. The optimal dose for beginners – 50 mg per day. Start with the lowest dose rate increasing during the first week to the optimum. In the penultimate week of the start to gradually reduce the dose to the complete abolition in the next two weeks.
  5. On completion of the course start taking testosterone boosters within 3-4 weeks, to restore natural testosterone.
  6. To maximize the effectiveness of the course, take a complex of sports nutrition for muscle mass set and follow a diet for a set of muscle mass.
  7. Be sure to consult a specialist before taking oxymetholone.

Combined courses

Oxymetholone well with certain injectable drugs, but do not combine it with the 17-alpha-alkylated steroids, as it doubles the load on the liver. Oxymetholone often used for so-called “fast start” (anabolic effect begins to manifest itself very quickly), followed by transfer to other drugs. The combination allows to achieve the best effect, due to the fact that oxymetholone reduces the concentration of sex hormone binding globulin, increasing the free fraction of other hormones. Given that Oxymetholone has a low affinity for the androgen receptor (bad contact them) vysokoandrogennye other hormones can have a full length action by means of interaction with these receptors without competing with Oxymetholone.

  • For muscle recruitment Oxymetholone combined with boldenone, Primobolan or trenbolone.
  • For drying and relief oxymetholone combined with Anavar.